July 28, 2022 7:44am

Determine the session

Pre-open indications: 5 Negative Indications and 1 Puff/Pump/Promote

Earnings today: Ultragenyx (RARE) and Alnylam Pharmaceuticals (ALNY) on Thursday 7/28

RMi outlines a daily bell ringing of “indications” about what you need to know; it’s what could happen or materialize after the opening and what might happen during the session.

What I provide is a trusted source of share pricing intelligence – it’s more than opinion, I deal in the facts and numbers that back them up.

The 8:00 A.M., ET edition


Remember that overnight and pre-open actions in futures don't necessarily translate into actual trading in the coming day’s session.

 

Dow futures are DOWN -0.14% or (-43 points), S&P futures are DOWN -0.24% (-9 points) and NASDAQ futures are DOWN -0.60% (-76 points) early in the pre-open – so far,

 

Stock futures moved lower Thursday

European markets were mixed,

Asia-Pacific markets were mostly higher.

 

Henry’omics:

U.S. equities and even the cell and gene therapy sector climbed Wednesday even as the Fed hiked. The Dow closed UP +436.05points (+1.37%); the S&P closed UP +102.50 points (+2.61%) while the Nasdaq closed UP +469.85 points (+4.06%)

Economic Data Docket: Q2 GDP - U.S. economic growth fell 0.9% in the second quarter, the Bureau of Economic Analysis reported. The Dow estimate was for a gain of 0.3%. Q1 GDP declined by 1.6%.

 

RegMed Investors’ (RMi) closing bell: “a share pricing roller coaster session. A mixed picture of the cell and gene therapy sector as earnings season begins tomorrow with Ultragenyx (RARE) and Alnylam Pharmaceuticals (ALNY) releases.” …  https://www.regmedinvestors.com/articles/12536

Ebb and flow –

Q3/22 – 1 holiday, 8 negative and 10 positive closes

Q2/22 –

June – 1 holiday, 9 positive and 11 negative closes

·         May - 11 positive and 10 negative closes

·         April - 1 holiday, 6 positive and 13 negative closes

Q1/22:

·         March – 13 negative and 10 positive closes

·         February stats: 11 negative, 8 positive closes and 1 holiday

·         January stats: 2 holidays, 1 neutral, 13 negative and 6 positive closes

 

Companies in my headlights – It’s your decision; I provide ideas and context: INDICATIONS

Negative indications:

Alnylam Pharmaceuticals (ALNY) closed up +$1.97 to $141.97 with a negative -$0.66 or -0.46% as earnings will be released today,

CRISPR Therapeutics (CRSP) closed up +$1.81 to $78.93 with a negative -$0.23 or -0.29% pre-open indication,

Verve Therapeutics (VERV) closed up +$1.04 to $29.55 after Tuesday’s -$1.27 to $28.51 and Monday’s -$0.83 with a negative $0.71 or -2.40% pre-open indication,

Editas Medicine (EDIT) closed up +$0.60 to $16.84 after Tuesday’s -$0.11, Monday’s +0.40 after Friday’s -$1.10 <52-week low of $9.59> and last Thursday’s -$0.36 with a negative -$0.55 or -3.27% pre-open indication,

Sage Therapeutics (SAGE) closed up +$0.19 to $34.69 with a negative -$1.24 or -3.57% pre-open indication,

 

Puff/Pump and Promote: Maintaining SELL

Biostage (OTCQB: BSTG) closed down -$0.05 with 545 shares traded after Tuesday $0.00 with 0 shares traded, Monday’s down -$0.45 to $4.95 with 974 shares traded, Friday’s +$0.30 to $5.40 with 998 shares traded and last Thursday’s +$0.09 with 1,018 shares traded <3 mo. Average = 1,326 shares>

·         BSTG seems to have the ONLY avenue to finance to utilize non-U.S. Chinese investors?

·         How much lipstick is a lot on this pig with an almost 4-year-old IND and NO clinical trial initiation?

·         WATCH and be ready for a BIG reverse of shares to enable offering from multiple private placements as it tries to facilitate an offering with Newbridge Securities

 

The BOTTOM LINE: I try to keep it simple … and short!

WHAT changes … NOT much although its earnings season beginning today …

Sector equity pricing are trending in a roller coaster fashion, currently being at the mercy of electronic trading, inflation, interest rates and earnings.

Sector expectations are really low as earnings season begins this week – RARE and ALNY on Thursday; remember, a little bit of good news can go a long way when you have low expectations.

When a cell and gene therapy sector equity sells-off to or below a buy point, investors face a tough decision: hold tight, exit or trim the position. There's not necessarily a "right" answer. Sometimes the stock will bounce right back, others will keep falling — perhaps after briefly bouncing. A more-cautious approach may make more sense in the current volatile market.

We are up, down, up and down – it gets tiring! Portfolios are wailing, not crying.

We always need a … villain and they are multiplying – low volume as “Earnings’ season is coming, investors NEED to focus on LPS (loss-per-share), collaboration revenues and cash positions i.e., runways”.

Upcoming earnings announcements: Sage Therapeutics (SAGE) on Tuesday, 8/2 and AxoGen (AXGN), Vericel (VCEL) and MiMedx (MDXG), Editas Medicine (EDIT), Fate Therapeutics (FATE) on Wednesday, 8/3 and Ionis Pharmaceuticals (IONS) on 8/9,

Investors are going to need to prepare for another reporting cycle to confirm whether or not a bottom is even close to happening.

There is VALUE out there however, it’s about playing or betting the timing of the sector.

So be extra cautious for the next few days. If you do make new purchases, look for early buying opportunities and try to buy as close to those entries as possible. <IBD>

Whether information or intelligence is good, bad or somewhere in between; RMi’s daily report is a primer that may say little or a lot; yet it serves as insurance that all indications are being examined and evaluated.

 

Opinions expressed are those of the author and are subject to change, and not intended to be a forecast of future events, a guarantee of future results, nor investment advice.

All investments are subject to risks. Investors should consider investment objectives.

Regulation Analyst Certification (Reg AC): The research analyst primarily responsible for the content of this report certifies the following under Reg AC: I hereby certify that all views expressed in this report accurately reflect my personal views about the subject company or companies and its or their securities. I also certify that no part of my compensation was, is or will be, directly or indirectly, related to the specific recommendations or views expressed in this report.

Henry McCusker, the editor and publisher of RegMed Investors does not hold or have positions securities referred to in this publication.