RegMed Investors’ (RMi) pre-open: gobble, gobble

November 21, 2023 7:36am

Upsides are scattered like grain for the fattened turkey equities to be eaten by Pacman electronic trading

Pre-Open Indications: 2 Sell into Strength, 3 Negative and 1 Positive

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I’m out of here until Friday’s close as markets are in a shortened trading week due to the Thanksgiving holiday on Thursday, followed by a 1 p.m. E.T. close on Friday.

I say today what others won't, so you can do what others can't whether information or intelligence is good, bad or somewhere in between; I put into context what is relevant and useful for investors.

The pre-open Dow futures are DOWN -0.17% or -60 points), the S&P is DOWN -0.14% or (-6 points) as the Nasdaq is DOWN -0.13% or -21 points)

Stock futures were down slightly Tuesday,

European markets were mixed,

Asia-Pacific markets were mostly up.

Henry’omics:

We need to more than consider the economic environment - rising rates and inflation to comprehend the micro re “our” universe of cell and gene therapy companies …

Indexes jumped Monday to start a holiday shortened week … as the Dow closed UP +203.76 points or +0.58%, the S&P closed UP +33.36 points or +0.74% while the Nasdaq closed UP +159.05 points or +1.13%.

Economic Data Docket: the minutes from the Fed’s Oct. 31 to Nov. 1 policy meeting; seeking a clue from policymakers’ rate decision

Monday, RegMed Investors (RMi) Closing Bell: “a dramatic sector equity uplift, don’t ignore the dangers of this market and sector as disruption will come from many directions. Short week became even shorter <for me> to enjoy a few sessions without thinking.” … https://www.regmedinvestors.com/articles/13215

Q4: November – 8 positive and 6 negative closes

·         October – 1 sick day, 9 positive and 12 negative closes

Companies in my headlights – It’s your decision; I provide ideas and context: looking for lost SHEAP …

I post about “indication intelligence” devoting my time to collection and analysis of information to assist investors with insight into sector vulnerabilities and strengths. A dictionary definition of “indicate” refers to something less than a certainty; an indication could be a signal of being oversold or overbought, a recommendation, or grounds for inferring or a basis for believing.

Sell into Strength Indication:

Monday’s closing price, some Friday. Thursday Wednesday and last Tuesday’s closing “numbers” with aftermarket dollar ($) and cent ($0.00) value and percentage (%)

Beam Therapeutics (BEAM) closed up +$3.39 after Friday’s +$2.68, Thursday’s -$0.36, Wednesday’s +$0.60 and last Tuesday’s +$2.61 with a positive +$0.24 or +0.78% pre-open indication.

Blueprint Medicine (BPMC) closed up +$2.22 after Friday’s +$1.04, Thursday’s -$1.05, Wednesday’s -$1.06 and last Tuesday’s +$5.87 with a positive +$0.07 or +0.11% aftermarket indication.

Negative Indications:

Monday’s closing price, some Friday, Thursday, Wednesday, Tuesday, Monday’s closing “numbers” with aftermarket dollar ($) and cent ($0.00) value and percentage (%)

Alnylam Pharmaceuticals (ALNY) closed up +$1.53 after Friday’s -$5.24, Thursday’s -$2.08, Wednesday’s +$1.06 and last Tuesday’s +$4.98 with a negative -$0.75 or -0.45% aftermarket indication.

Ultragenyx Pharmaceuticals (RARE) closed down -$0.62 after Friday’s +$1.02 with a positive -$0.35 or -0.89% pre-open indication.

BioLife Solutions (BLFS) closed up +$0.64 after Friday’s +$0.81, Thursday’s -$0.38 after Wednesday’s +$0.45 with a negative -$0.07 or -0.52% aftermarket indication.

Positive Indication:

Monday’s closing price, some Friday, Thursday, Wednesday, Tuesday, Monday’s closing “numbers” with aftermarket dollar ($) and cent ($0.00) value and percentage (%)

Intellia Therapeutics (NTLA) closed up +$2.16 after Friday’s +$2.10 after Thursday’s -$0.56 with a positive +$0.19 or +0.63% aftermarket indication.

The BOTTOM LINE:  I DON’T believe totally in … following i.e., believing in the market and sector's actions – it’s usually a signal to lighten the load of the sector’s upside movers.

• The historical pattern over the last five years suggests the shortened holiday week typically enjoys modest gains," <Quincy Krosby, chief global strategist for LPL Financial>
• However, I have concerns over the resiliency of upside moves that usually end in downward sells as the risk/reward profile doesn’t always compel elevated and “dramatic” i.e., sudden equity pricing.

I hate to be so negative or contrarian but, this is a NO spin zone and facts are its product; I am more frequently right than consequentially wrong as … I am mostly EARLY!

• Every time, I read there was more bullish action from last week and a strong positive Monday; that … “investors should be raising their market exposure… I recommend that when the trend strengthens – it’s time to lighten the load and sometimes “fold your <portfolio> cards”

Today’s relevancy from Monday’s session:

• The Nasdaq saw its highest close since July 31 while the S&P 500 registered its highest closing level since 8/1; while trading is expected to be muted for much of the week ahead of Thursday's U.S. Thanksgiving holiday.
• Investors should be very cautious, holding to some positions and building cash if possible!

So, it's time to think ahead to December. It's usually an important month for the Nasdaq.

• But, don’t FORGET portfolio tax selling and a bit of rebalancing
• And then comes January and with worries that the U.S. economy will be slowing down, the potential for continued Middle East violence and, of course, the real prospect of bitterly contested elections across all of the United States. <The Street>

Opinions expressed are those of the author and are subject to change, and not intended to be a forecast of future events, a guarantee of future results, nor investment advice. All investments are subject to risks. Investors should consider investment objectives.

Whether information or intelligence is good, bad or somewhere in between; I put into context what is relevant and useful for investors.  All investments are subject to risks. Investors should consider investment objectives.  Regulation Analyst Certification (Reg AC): The research analyst primarily responsible for the content of this report certifies the following under Reg AC: I hereby certify that all views expressed in this report accurately reflect my personal views about the subject company or companies and its or their securities. I also certify that no part of my compensation was, is or will be, directly or indirectly, related to the specific recommendations or views expressed in this report.

Henry McCusker, the editor and publisher of RegMed Investors could hold or have positions securities referred to in this publication and he will NOTIFY investors of holdings.