December 14, 2016 11:37am
BCLI closed at $2.16 and is UP +$0.47 or +21.84% to $2.63 after ALS presentation at the 27th International Symposium on ALS/MND
In the P2 trial, levels of neurotrophic factors and inflammatory markers were measured in cerebral-spinal fluid (CSF) samples collected from patients.
Pre-specified responder analyses from the P2 trial which examined percentage improvements in post treatment of Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R) slope compared to pre-treatment slope. These analyses showed that, in the NurOwn treated group, a greater number of patients achieved the high threshold of 100% improvement in the post-treatment vs. pre-treatment slope, compared with the placebo group.
These analyses showed that, in the NurOwn treated group, a greater number of patients achieved the high threshold of 100% improvement in the post-treatment vs. pre-treatment slope, compared with the placebo group.
The Bottom Line: In the samples of those patients treated with NurOwn, a statistically significant increase in levels of neurotrophic factors VEGF, HGF and LIF was observed from pre- to post-transplantation. There was also a statistically significant reduction in inflammatory markers (MCP-1 and SDF-1) over this period, in patients treated with NurOwn and this was not observed in the placebo group.
BCLI closed at $2.16 and is UP +$0.47 or +21.84% to $2.63
SELL into strength, BCLI’s pricing never holds …